| South Lyon to Secaucus (New Jersey) | 508.28 mi (818.00 km) |
| South Lyon to Security-Widefield (Colorado) | 1,131.01 mi (1,820.19 km) |
| South Lyon to Sedalia (Missouri) | 565.30 mi (909.77 km) |
| South Lyon to Sedro-Woolley (Washington) | 1,893.61 mi (3,047.47 km) |
| South Lyon to Seguin (Texas) | 1,192.79 mi (1,919.61 km) |
| South Lyon to Selden (New York) | 557.94 mi (897.92 km) |
| South Lyon to Selma (Alabama) | 718.21 mi (1,155.85 km) |
| South Lyon to Selma (California) | 1,944.27 mi (3,129.00 km) |
| South Lyon to Selma (Texas) | 1,205.77 mi (1,940.50 km) |
| South Lyon to Seminole (Florida) | 1,011.17 mi (1,627.33 km) |
| South Lyon to Seven Hills (Ohio) | 126.21 mi (203.12 km) |
| South Lyon to Seven Oaks (South Carolina) | 596.99 mi (960.76 km) |
| South Lyon to Severn (Maryland) | 430.15 mi (692.26 km) |
| South Lyon to Severna Park (Maryland) | 437.65 mi (704.34 km) |
| South Lyon to Sevierville (Tennessee) | 454.26 mi (731.05 km) |
