| South Lyon to Orangeburg (South Carolina) | 637.86 mi (1,026.54 km) |
| South Lyon to Orangevale (California) | 1,972.47 mi (3,174.38 km) |
| South Lyon to Orchards (Washington) | 1,923.54 mi (3,095.65 km) |
| South Lyon to Orcutt (California) | 2,034.58 mi (3,274.34 km) |
| South Lyon to Oregon (Ohio) | 57.03 mi (91.78 km) |
| South Lyon to Oregon (Wisconsin) | 293.02 mi (471.57 km) |
| South Lyon to Oregon City (Oregon) | 1,929.77 mi (3,105.66 km) |
| South Lyon to Orem (Utah) | 1,455.04 mi (2,341.66 km) |
| South Lyon to Orinda (California) | 2,040.67 mi (3,284.14 km) |
| South Lyon to Orland Park (Illinois) | 223.90 mi (360.33 km) |
| South Lyon to Orlando (Florida) | 974.84 mi (1,568.86 km) |
| South Lyon to Ormond Beach (Florida) | 920.49 mi (1,481.38 km) |
| South Lyon to Oro Valley (Arizona) | 1,642.05 mi (2,642.62 km) |
| South Lyon to Oroville (California) | 1,971.51 mi (3,172.83 km) |
| South Lyon to Oshkosh (Wisconsin) | 269.56 mi (433.81 km) |
