| South Euclid to Sacile | 4,414.42 mi (7,104.33 km) |
| South Euclid to Sala Consilina | 4,764.98 mi (7,668.49 km) |
| South Euclid to Salemi | 4,752.57 mi (7,648.52 km) |
| South Euclid to Salerno | 4,718.08 mi (7,593.01 km) |
| South Euclid to Salo | 4,349.11 mi (6,999.21 km) |
| South Euclid to Salsomaggiore Terme | 4,355.92 mi (7,010.17 km) |
| South Euclid to Saluzzo | 4,258.91 mi (6,854.06 km) |
| South Euclid to Salzano | 4,415.67 mi (7,106.33 km) |
| South Euclid to Samarate | 4,277.06 mi (6,883.27 km) |
| South Euclid to San Benedetto del Tronto | 4,589.08 mi (7,385.41 km) |
| South Euclid to San Biagio di Callalta | 4,420.43 mi (7,113.99 km) |
| South Euclid to San Bonifacio | 4,387.08 mi (7,060.33 km) |
| South Euclid to San Casciano in Val di Pesa | 4,449.83 mi (7,161.31 km) |
| South Euclid to San Cataldo | 4,818.09 mi (7,753.97 km) |
| South Euclid to San Cesareo | 4,589.58 mi (7,386.21 km) |
