| South Daytona to Southern Pines (North Carolina) | 426.81 mi (686.88 km) |
| South Daytona to Southfield (Michigan) | 928.22 mi (1,493.83 km) |
| South Daytona to Southgate (Michigan) | 909.24 mi (1,463.28 km) |
| South Daytona to Southlake (Texas) | 989.61 mi (1,592.62 km) |
| South Daytona to Spanaway (Washington) | 2,529.22 mi (4,070.39 km) |
| South Daytona to Spanish Fork (Utah) | 1,886.38 mi (3,035.83 km) |
| South Daytona to Spanish Lake (Missouri) | 847.53 mi (1,363.97 km) |
| South Daytona to Spanish Springs (Nevada) | 2,299.87 mi (3,701.28 km) |
| South Daytona to Sparks (Nevada) | 2,301.72 mi (3,704.26 km) |
| South Daytona to Spartanburg (South Carolina) | 402.86 mi (648.35 km) |
| South Daytona to Spearfish (South Dakota) | 1,636.88 mi (2,634.31 km) |
| South Daytona to Speedway (Indiana) | 792.31 mi (1,275.10 km) |
| South Daytona to Spencer (Iowa) | 1,243.75 mi (2,001.62 km) |
| South Daytona to Spokane (Washington) | 2,318.00 mi (3,730.46 km) |
| South Daytona to Spokane Valley (Washington) | 2,309.23 mi (3,716.35 km) |
