| South Charleston to Superior (Colorado) | 1,257.51 mi (2,023.76 km) |
| South Charleston to Superior (Wisconsin) | 780.77 mi (1,256.52 km) |
| South Charleston to Surprise (Arizona) | 1,739.40 mi (2,799.30 km) |
| South Charleston to Susanville (California) | 2,065.50 mi (3,324.10 km) |
| South Charleston to Sussex (Wisconsin) | 474.76 mi (764.06 km) |
| South Charleston to Suwanee (Georgia) | 324.23 mi (521.80 km) |
| South Charleston to Swansea (Illinois) | 447.61 mi (720.36 km) |
| South Charleston to Sweetwater (Florida) | 871.60 mi (1,402.71 km) |
| South Charleston to Sweetwater (Texas) | 1,125.70 mi (1,811.64 km) |
| South Charleston to Sycamore (Illinois) | 445.85 mi (717.53 km) |
| South Charleston to Sylacauga (Alabama) | 438.34 mi (705.45 km) |
| South Charleston to Sylvania (Ohio) | 255.44 mi (411.09 km) |
| South Charleston to Syosset (New York) | 469.35 mi (755.35 km) |
| South Charleston to Syracuse (New York) | 436.34 mi (702.22 km) |
| South Charleston to Syracuse (Utah) | 1,616.17 mi (2,600.97 km) |
