| South Charleston to Storm Lake (Iowa) | 767.00 mi (1,234.37 km) |
| South Charleston to Storrs (Connecticut) | 554.29 mi (892.04 km) |
| South Charleston to Stoughton (Wisconsin) | 504.75 mi (812.31 km) |
| South Charleston to Stow (Ohio) | 196.37 mi (316.03 km) |
| South Charleston to Streamwood (Illinois) | 425.19 mi (684.27 km) |
| South Charleston to Streator (Illinois) | 423.88 mi (682.17 km) |
| South Charleston to Streetsboro (Ohio) | 201.12 mi (323.68 km) |
| South Charleston to Strongsville (Ohio) | 205.31 mi (330.42 km) |
| South Charleston to Stuart (Florida) | 774.86 mi (1,247.01 km) |
| South Charleston to Stuarts Draft (Virginia) | 147.26 mi (237.00 km) |
| South Charleston to Sturgis (Michigan) | 308.75 mi (496.88 km) |
| South Charleston to Suamico (Wisconsin) | 544.74 mi (876.67 km) |
| South Charleston to Sudley (Virginia) | 229.99 mi (370.14 km) |
| South Charleston to Suffern (New York) | 445.45 mi (716.88 km) |
| South Charleston to Suffolk (Virginia) | 300.49 mi (483.58 km) |
