| South Charleston to Stephenville (Texas) | 1,020.72 mi (1,642.69 km) |
| South Charleston to Sterling (Colorado) | 1,153.16 mi (1,855.83 km) |
| South Charleston to Sterling (Illinois) | 484.55 mi (779.81 km) |
| South Charleston to Sterling (Virginia) | 236.96 mi (381.35 km) |
| South Charleston to Sterling Heights (Michigan) | 300.88 mi (484.21 km) |
| South Charleston to Steubenville (Ohio) | 150.86 mi (242.79 km) |
| South Charleston to Stevens Point (Wisconsin) | 588.64 mi (947.33 km) |
| South Charleston to Stevenson Ranch (California) | 2,055.88 mi (3,308.61 km) |
| South Charleston to Stillwater (Minnesota) | 736.44 mi (1,185.18 km) |
| South Charleston to Stillwater (Oklahoma) | 857.49 mi (1,380.00 km) |
| South Charleston to Stockbridge (Georgia) | 361.29 mi (581.44 km) |
| South Charleston to Stockton (California) | 2,134.47 mi (3,435.09 km) |
| South Charleston to Stone Ridge (Virginia) | 228.12 mi (367.12 km) |
| South Charleston to Stonecrest (Georgia) | 349.12 mi (561.86 km) |
| South Charleston to Stony Brook (New York) | 489.88 mi (788.38 km) |
