| South Charleston to Santa Paula (California) | 2,082.45 mi (3,351.38 km) |
| South Charleston to Santa Rosa (California) | 2,200.98 mi (3,542.13 km) |
| South Charleston to Santaquin (Utah) | 1,607.79 mi (2,587.49 km) |
| South Charleston to Santee (California) | 2,004.84 mi (3,226.48 km) |
| South Charleston to Sapulpa (Oklahoma) | 807.27 mi (1,299.18 km) |
| South Charleston to Saraland (Alabama) | 632.08 mi (1,017.24 km) |
| South Charleston to Sarasota (Florida) | 761.80 mi (1,226.00 km) |
| South Charleston to Sarasota Springs (Florida) | 763.63 mi (1,228.95 km) |
| South Charleston to Saratoga (California) | 2,184.20 mi (3,515.13 km) |
| South Charleston to Saratoga Springs (New York) | 528.21 mi (850.08 km) |
| South Charleston to Saratoga Springs (Utah) | 1,611.77 mi (2,593.89 km) |
| South Charleston to Sartell (Minnesota) | 814.03 mi (1,310.05 km) |
| South Charleston to Satellite Beach (Florida) | 705.22 mi (1,134.93 km) |
| South Charleston to Sauk Rapids (Minnesota) | 810.55 mi (1,304.45 km) |
| South Charleston to Sault Ste. Marie (Michigan) | 578.36 mi (930.79 km) |
