| South Charleston to Oskaloosa (Iowa) | 614.03 mi (988.19 km) |
| South Charleston to Oswego (Illinois) | 419.41 mi (674.97 km) |
| South Charleston to Oswego (New York) | 445.65 mi (717.21 km) |
| South Charleston to Otsego (Minnesota) | 776.28 mi (1,249.29 km) |
| South Charleston to Ottawa (Illinois) | 430.61 mi (693.00 km) |
| South Charleston to Ottawa (Kansas) | 732.43 mi (1,178.73 km) |
| South Charleston to Ottumwa (Iowa) | 597.96 mi (962.33 km) |
| South Charleston to Overland (Missouri) | 468.25 mi (753.58 km) |
| South Charleston to Overland Park (Kansas) | 700.71 mi (1,127.68 km) |
| South Charleston to Overlea (Maryland) | 288.41 mi (464.15 km) |
| South Charleston to Oviedo (Florida) | 669.83 mi (1,077.99 km) |
| South Charleston to Owasso (Oklahoma) | 787.73 mi (1,267.72 km) |
| South Charleston to Owatonna (Minnesota) | 717.26 mi (1,154.31 km) |
| South Charleston to Owensboro (Kentucky) | 296.62 mi (477.37 km) |
| South Charleston to Owings Mills (Maryland) | 274.93 mi (442.45 km) |
