| South Charleston to Des Plaines (Illinois) | 414.12 mi (666.46 km) |
| South Charleston to Desert Hot Springs (California) | 1,954.85 mi (3,146.02 km) |
| South Charleston to DeSoto (Texas) | 938.64 mi (1,510.59 km) |
| South Charleston to Destin (Florida) | 612.18 mi (985.22 km) |
| South Charleston to Destrehan (Louisiana) | 760.78 mi (1,224.36 km) |
| South Charleston to Detroit (Michigan) | 288.57 mi (464.41 km) |
| South Charleston to Diamond Bar (California) | 2,022.79 mi (3,255.36 km) |
| South Charleston to Diamond Springs (California) | 2,098.79 mi (3,377.67 km) |
| South Charleston to Dickinson (North Dakota) | 1,218.14 mi (1,960.41 km) |
| South Charleston to Dickinson (Texas) | 979.33 mi (1,576.08 km) |
| South Charleston to Dickson (Tennessee) | 348.49 mi (560.84 km) |
| South Charleston to Difficult Run (Virginia) | 238.93 mi (384.52 km) |
| South Charleston to Dinuba (California) | 2,056.56 mi (3,309.71 km) |
| South Charleston to Discovery Bay (California) | 2,150.86 mi (3,461.48 km) |
| South Charleston to Dix Hills (New York) | 477.24 mi (768.05 km) |
