| South Bend to Superior (Colorado) | 993.17 mi (1,598.35 km) |
| South Bend to Superior (Wisconsin) | 450.43 mi (724.89 km) |
| South Bend to Surprise (Arizona) | 1,527.16 mi (2,457.73 km) |
| South Bend to Susanville (California) | 1,779.77 mi (2,864.26 km) |
| South Bend to Sussex (Wisconsin) | 141.68 mi (228.01 km) |
| South Bend to Suwanee (Georgia) | 540.35 mi (869.61 km) |
| South Bend to Swansea (Illinois) | 291.85 mi (469.68 km) |
| South Bend to Sweetwater (Florida) | 1,148.72 mi (1,848.68 km) |
| South Bend to Sweetwater (Texas) | 1,003.81 mi (1,615.47 km) |
| South Bend to Sycamore (Illinois) | 126.13 mi (202.98 km) |
| South Bend to Sylacauga (Alabama) | 587.20 mi (945.01 km) |
| South Bend to Sylvania (Ohio) | 132.11 mi (212.62 km) |
| South Bend to Syosset (New York) | 665.32 mi (1,070.74 km) |
| South Bend to Syracuse (New York) | 525.16 mi (845.17 km) |
| South Bend to Syracuse (Utah) | 1,333.16 mi (2,145.52 km) |
