| South Bend to Siloam Springs (Arkansas) | 583.62 mi (939.25 km) |
| South Bend to Silver Firs (Washington) | 1,793.75 mi (2,886.77 km) |
| South Bend to Silver Spring (Maryland) | 520.61 mi (837.84 km) |
| South Bend to Silver Springs Shores (Florida) | 900.24 mi (1,448.79 km) |
| South Bend to Silverdale (Washington) | 1,818.52 mi (2,926.63 km) |
| South Bend to Silverton (Oregon) | 1,833.34 mi (2,950.47 km) |
| South Bend to Simi Valley (California) | 1,829.52 mi (2,944.33 km) |
| South Bend to Simpsonville (South Carolina) | 527.02 mi (848.16 km) |
| South Bend to Sioux City (Iowa) | 521.71 mi (839.60 km) |
| South Bend to Sioux Falls (South Dakota) | 546.93 mi (880.21 km) |
| South Bend to Skokie (Illinois) | 79.64 mi (128.16 km) |
| South Bend to Sleepy Hollow (New York) | 643.38 mi (1,035.42 km) |
| South Bend to Slidell (Louisiana) | 810.78 mi (1,304.82 km) |
| South Bend to Smithfield (North Carolina) | 603.03 mi (970.48 km) |
| South Bend to Smithfield (Utah) | 1,312.43 mi (2,112.15 km) |
