| South Bend to Scottsbluff (Nebraska) | 894.76 mi (1,439.98 km) |
| South Bend to Scottsboro (Alabama) | 486.07 mi (782.26 km) |
| South Bend to Scottsdale (Arizona) | 1,497.48 mi (2,409.96 km) |
| South Bend to Scranton (Pennsylvania) | 548.40 mi (882.57 km) |
| South Bend to Seabrook (Maryland) | 529.62 mi (852.34 km) |
| South Bend to Seabrook (Texas) | 968.70 mi (1,558.98 km) |
| South Bend to Seaford (New York) | 667.56 mi (1,074.34 km) |
| South Bend to Seagoville (Texas) | 840.68 mi (1,352.94 km) |
| South Bend to Seal Beach (California) | 1,810.51 mi (2,913.74 km) |
| South Bend to Searcy (Arkansas) | 533.69 mi (858.89 km) |
| South Bend to Seaside (California) | 1,922.53 mi (3,094.02 km) |
| South Bend to SeaTac (Washington) | 1,800.75 mi (2,898.03 km) |
| South Bend to Seattle (Washington) | 1,801.86 mi (2,899.82 km) |
| South Bend to Sebastian (Florida) | 1,014.06 mi (1,631.97 km) |
| South Bend to Sebring (Florida) | 1,018.18 mi (1,638.61 km) |
