| South Bend to Enterprise (Nevada) | 1,598.58 mi (2,572.66 km) |
| South Bend to Enumclaw (Washington) | 1,786.51 mi (2,875.11 km) |
| South Bend to Ephrata (Pennsylvania) | 536.34 mi (863.15 km) |
| South Bend to Erie (Colorado) | 985.39 mi (1,585.84 km) |
| South Bend to Erie (Pennsylvania) | 320.05 mi (515.07 km) |
| South Bend to Erlanger (Kentucky) | 204.40 mi (328.94 km) |
| South Bend to Escanaba (Michigan) | 284.24 mi (457.44 km) |
| South Bend to Escondido (California) | 1,779.33 mi (2,863.56 km) |
| South Bend to Española (New Mexico) | 1,132.13 mi (1,821.98 km) |
| South Bend to Essex (Maryland) | 541.34 mi (871.20 km) |
| South Bend to Essex Junction (Vermont) | 690.85 mi (1,111.82 km) |
| South Bend to Estelle (Louisiana) | 845.03 mi (1,359.94 km) |
| South Bend to Estero (Florida) | 1,083.87 mi (1,744.32 km) |
| South Bend to Euclid (Ohio) | 245.38 mi (394.90 km) |
| South Bend to Eufaula (Alabama) | 677.62 mi (1,090.52 km) |
