| South Bend to Elyria (Ohio) | 216.35 mi (348.18 km) |
| South Bend to Emeryville (California) | 1,917.58 mi (3,086.05 km) |
| South Bend to Emmaus (Pennsylvania) | 565.93 mi (910.78 km) |
| South Bend to Emporia (Kansas) | 571.15 mi (919.17 km) |
| South Bend to Encinitas (California) | 1,791.75 mi (2,883.55 km) |
| South Bend to Endicott (New York) | 525.44 mi (845.62 km) |
| South Bend to Endwell (New York) | 527.59 mi (849.08 km) |
| South Bend to Englewood (Colorado) | 989.36 mi (1,592.22 km) |
| South Bend to Englewood (Florida) | 1,039.99 mi (1,673.71 km) |
| South Bend to Englewood (New Jersey) | 640.16 mi (1,030.23 km) |
| South Bend to Englewood (Ohio) | 161.94 mi (260.62 km) |
| South Bend to Enid (Oklahoma) | 720.28 mi (1,159.18 km) |
| South Bend to Ennis (Texas) | 861.56 mi (1,386.55 km) |
| South Bend to Ensley (Florida) | 772.46 mi (1,243.16 km) |
| South Bend to Enterprise (Alabama) | 715.44 mi (1,151.40 km) |
