| Sioux Falls to Sestu | 5,081.11 mi (8,177.26 km) |
| Sioux Falls to Settimo Torinese | 4,759.65 mi (7,659.91 km) |
| Sioux Falls to Seveso | 4,786.11 mi (7,702.50 km) |
| Sioux Falls to Sezze | 5,125.56 mi (8,248.79 km) |
| Sioux Falls to Siano | 5,219.36 mi (8,399.75 km) |
| Sioux Falls to Siena | 4,974.51 mi (8,005.70 km) |
| Sioux Falls to Signa | 4,944.01 mi (7,956.61 km) |
| Sioux Falls to Silea | 4,897.81 mi (7,882.26 km) |
| Sioux Falls to Silvi Paese | 5,112.34 mi (8,227.51 km) |
| Sioux Falls to Sinalunga | 4,993.98 mi (8,037.04 km) |
| Sioux Falls to Siniscola | 5,043.93 mi (8,117.42 km) |
| Sioux Falls to Sinnai | 5,085.29 mi (8,183.98 km) |
| Sioux Falls to Siracusa | 5,427.81 mi (8,735.22 km) |
| Sioux Falls to Solaro | 4,785.49 mi (7,701.50 km) |
| Sioux Falls to Soliera | 4,892.54 mi (7,873.79 km) |
