| Sioux Falls to Savignano sul Rubicone | 4,976.05 mi (8,008.17 km) |
| Sioux Falls to Savona | 4,823.70 mi (7,762.99 km) |
| Sioux Falls to Scafati | 5,215.61 mi (8,393.72 km) |
| Sioux Falls to Scalea | 5,308.84 mi (8,543.75 km) |
| Sioux Falls to Scandiano | 4,890.88 mi (7,871.12 km) |
| Sioux Falls to Scandicci | 4,948.62 mi (7,964.03 km) |
| Sioux Falls to Schio | 4,862.05 mi (7,824.71 km) |
| Sioux Falls to Sciacca | 5,322.17 mi (8,565.20 km) |
| Sioux Falls to Scicli | 5,419.55 mi (8,721.93 km) |
| Sioux Falls to Scordia | 5,399.68 mi (8,689.94 km) |
| Sioux Falls to Scorze | 4,895.16 mi (7,878.00 km) |
| Sioux Falls to Sedico | 4,869.01 mi (7,835.91 km) |
| Sioux Falls to Sedriano | 4,787.32 mi (7,704.44 km) |
| Sioux Falls to Segni | 5,114.80 mi (8,231.48 km) |
| Sioux Falls to Segrate | 4,798.87 mi (7,723.03 km) |
