| Sioux Falls to Sacile | 4,890.06 mi (7,869.80 km) |
| Sioux Falls to Sala Consilina | 5,272.34 mi (8,485.02 km) |
| Sioux Falls to Salemi | 5,295.94 mi (8,522.99 km) |
| Sioux Falls to Salerno | 5,227.78 mi (8,413.31 km) |
| Sioux Falls to Salo | 4,838.11 mi (7,786.18 km) |
| Sioux Falls to Salsomaggiore Terme | 4,854.91 mi (7,813.22 km) |
| Sioux Falls to Saluzzo | 4,771.69 mi (7,679.30 km) |
| Sioux Falls to Salzano | 4,897.27 mi (7,881.39 km) |
| Sioux Falls to Samarate | 4,774.56 mi (7,683.91 km) |
| Sioux Falls to San Benedetto del Tronto | 5,084.40 mi (8,182.56 km) |
| Sioux Falls to San Biagio di Callalta | 4,899.26 mi (7,884.59 km) |
| Sioux Falls to San Bonifacio | 4,874.15 mi (7,844.19 km) |
| Sioux Falls to San Casciano in Val di Pesa | 4,953.12 mi (7,971.27 km) |
| Sioux Falls to San Cataldo | 5,357.63 mi (8,622.27 km) |
| Sioux Falls to San Cesareo | 5,100.38 mi (8,208.27 km) |
