| Shepherdsville to Superior (Colorado) | 1,051.98 mi (1,692.99 km) |
| Shepherdsville to Superior (Wisconsin) | 684.00 mi (1,100.80 km) |
| Shepherdsville to Surprise (Arizona) | 1,522.14 mi (2,449.64 km) |
| Shepherdsville to Susanville (California) | 1,864.73 mi (3,000.99 km) |
| Shepherdsville to Sussex (Wisconsin) | 379.82 mi (611.26 km) |
| Shepherdsville to Suwanee (Georgia) | 286.46 mi (461.02 km) |
| Shepherdsville to Swansea (Illinois) | 235.74 mi (379.39 km) |
| Shepherdsville to Sweetwater (Florida) | 898.69 mi (1,446.31 km) |
| Shepherdsville to Sweetwater (Texas) | 911.94 mi (1,467.63 km) |
| Shepherdsville to Sycamore (Illinois) | 319.07 mi (513.50 km) |
| Shepherdsville to Sylacauga (Alabama) | 333.36 mi (536.49 km) |
| Shepherdsville to Sylvania (Ohio) | 278.43 mi (448.08 km) |
| Shepherdsville to Syosset (New York) | 679.45 mi (1,093.47 km) |
| Shepherdsville to Syracuse (New York) | 611.12 mi (983.50 km) |
| Shepherdsville to Syracuse (Utah) | 1,415.90 mi (2,278.67 km) |
