| Shepherdsville to Storm Lake (Iowa) | 594.42 mi (956.63 km) |
| Shepherdsville to Storrs (Connecticut) | 759.38 mi (1,222.11 km) |
| Shepherdsville to Stoughton (Wisconsin) | 388.36 mi (625.01 km) |
| Shepherdsville to Stow (Ohio) | 316.71 mi (509.70 km) |
| Shepherdsville to Streamwood (Illinois) | 308.33 mi (496.21 km) |
| Shepherdsville to Streator (Illinois) | 273.73 mi (440.52 km) |
| Shepherdsville to Streetsboro (Ohio) | 323.06 mi (519.91 km) |
| Shepherdsville to Strongsville (Ohio) | 308.74 mi (496.86 km) |
| Shepherdsville to Stuart (Florida) | 809.65 mi (1,303.00 km) |
| Shepherdsville to Stuarts Draft (Virginia) | 362.83 mi (583.92 km) |
| Shepherdsville to Sturgis (Michigan) | 264.21 mi (425.20 km) |
| Shepherdsville to Suamico (Wisconsin) | 475.83 mi (765.78 km) |
| Shepherdsville to Sudley (Virginia) | 447.68 mi (720.47 km) |
| Shepherdsville to Suffern (New York) | 652.12 mi (1,049.48 km) |
| Shepherdsville to Suffolk (Virginia) | 505.40 mi (813.37 km) |
