| Shepherdsville to St. George (Utah) | 1,522.94 mi (2,450.94 km) |
| Shepherdsville to St. Helens (Oregon) | 1,964.65 mi (3,161.80 km) |
| Shepherdsville to St. James (New York) | 698.21 mi (1,123.66 km) |
| Shepherdsville to St. John (Indiana) | 256.97 mi (413.56 km) |
| Shepherdsville to St. Joseph (Missouri) | 505.51 mi (813.55 km) |
| Shepherdsville to St. Louis (Missouri) | 250.47 mi (403.09 km) |
| Shepherdsville to St. Louis Park (Minnesota) | 623.27 mi (1,003.06 km) |
| Shepherdsville to St. Marys (Georgia) | 551.75 mi (887.95 km) |
| Shepherdsville to St. Marys (Pennsylvania) | 450.03 mi (724.26 km) |
| Shepherdsville to St. Matthews (Kentucky) | 18.85 mi (30.34 km) |
| Shepherdsville to St. Michael (Minnesota) | 646.92 mi (1,041.12 km) |
| Shepherdsville to St. Paul (Minnesota) | 614.75 mi (989.34 km) |
| Shepherdsville to St. Peter (Minnesota) | 613.59 mi (987.48 km) |
| Shepherdsville to St. Peters (Missouri) | 271.35 mi (436.70 km) |
| Shepherdsville to St. Petersburg (Florida) | 725.51 mi (1,167.59 km) |
