| Shepherdsville to Smyrna (Delaware) | 551.87 mi (888.15 km) |
| Shepherdsville to Smyrna (Georgia) | 292.13 mi (470.13 km) |
| Shepherdsville to Smyrna (Tennessee) | 146.33 mi (235.50 km) |
| Shepherdsville to Snellville (Georgia) | 300.40 mi (483.45 km) |
| Shepherdsville to Snoqualmie (Washington) | 1,927.96 mi (3,102.75 km) |
| Shepherdsville to Snyder (Texas) | 929.83 mi (1,496.42 km) |
| Shepherdsville to Socastee (South Carolina) | 477.83 mi (769.00 km) |
| Shepherdsville to Socorro (Texas) | 1,242.64 mi (1,999.84 km) |
| Shepherdsville to Soddy-Daisy (Tennessee) | 190.48 mi (306.54 km) |
| Shepherdsville to Solana Beach (California) | 1,799.50 mi (2,896.01 km) |
| Shepherdsville to Soledad (California) | 1,952.13 mi (3,141.65 km) |
| Shepherdsville to Solon (Ohio) | 326.54 mi (525.51 km) |
| Shepherdsville to Somers Point (New Jersey) | 605.32 mi (974.16 km) |
| Shepherdsville to Somerset (Kentucky) | 86.11 mi (138.57 km) |
| Shepherdsville to Somerset (New Jersey) | 623.70 mi (1,003.74 km) |
