| Shepherdsville to Silver Firs (Washington) | 1,944.94 mi (3,130.08 km) |
| Shepherdsville to Silver Spring (Maryland) | 474.49 mi (763.62 km) |
| Shepherdsville to Silver Springs Shores (Florida) | 648.32 mi (1,043.37 km) |
| Shepherdsville to Silverdale (Washington) | 1,967.98 mi (3,167.16 km) |
| Shepherdsville to Silverton (Oregon) | 1,960.94 mi (3,155.83 km) |
| Shepherdsville to Simi Valley (California) | 1,852.37 mi (2,981.11 km) |
| Shepherdsville to Simpsonville (South Carolina) | 295.29 mi (475.23 km) |
| Shepherdsville to Sioux City (Iowa) | 643.63 mi (1,035.82 km) |
| Shepherdsville to Sioux Falls (South Dakota) | 692.42 mi (1,114.34 km) |
| Shepherdsville to Skokie (Illinois) | 300.20 mi (483.12 km) |
| Shepherdsville to Sleepy Hollow (New York) | 665.31 mi (1,070.71 km) |
| Shepherdsville to Slidell (Louisiana) | 580.34 mi (933.97 km) |
| Shepherdsville to Smithfield (North Carolina) | 441.10 mi (709.88 km) |
| Shepherdsville to Smithfield (Utah) | 1,404.33 mi (2,260.05 km) |
| Shepherdsville to Smithville (Missouri) | 488.20 mi (785.69 km) |
