| Shepherdsville to Shelbyville (Tennessee) | 176.50 mi (284.04 km) |
| Shepherdsville to Shelton (Connecticut) | 705.95 mi (1,136.12 km) |
| Shepherdsville to Shelton (Washington) | 1,984.96 mi (3,194.48 km) |
| Shepherdsville to Shenandoah (Louisiana) | 604.73 mi (973.22 km) |
| Shepherdsville to Sheridan (Wyoming) | 1,194.03 mi (1,921.61 km) |
| Shepherdsville to Sherman (Texas) | 681.31 mi (1,096.46 km) |
| Shepherdsville to Sherrelwood (Colorado) | 1,043.52 mi (1,679.38 km) |
| Shepherdsville to Sherwood (Arkansas) | 421.14 mi (677.76 km) |
| Shepherdsville to Sherwood (Oregon) | 1,964.58 mi (3,161.68 km) |
| Shepherdsville to Shiloh (Illinois) | 232.04 mi (373.44 km) |
| Shepherdsville to Shiloh (Ohio) | 149.35 mi (240.36 km) |
| Shepherdsville to Shiloh (Pennsylvania) | 497.66 mi (800.90 km) |
| Shepherdsville to Shirley (New York) | 711.18 mi (1,144.54 km) |
| Shepherdsville to Shively (Kentucky) | 16.12 mi (25.94 km) |
| Shepherdsville to Shoreline (Washington) | 1,952.95 mi (3,142.97 km) |
