| Shepherdsville to Seymour (Indiana) | 67.55 mi (108.72 km) |
| Shepherdsville to Seymour (Tennessee) | 180.32 mi (290.20 km) |
| Shepherdsville to Shady Hills (Florida) | 686.25 mi (1,104.41 km) |
| Shepherdsville to Shafter (California) | 1,853.15 mi (2,982.35 km) |
| Shepherdsville to Shaker Heights (Ohio) | 326.88 mi (526.07 km) |
| Shepherdsville to Shakopee (Minnesota) | 618.15 mi (994.82 km) |
| Shepherdsville to Sharon (Pennsylvania) | 356.47 mi (573.68 km) |
| Shepherdsville to Sharonville (Ohio) | 113.83 mi (183.19 km) |
| Shepherdsville to Shasta Lake (California) | 1,954.77 mi (3,145.89 km) |
| Shepherdsville to Shawnee (Kansas) | 497.39 mi (800.47 km) |
| Shepherdsville to Shawnee (Oklahoma) | 649.65 mi (1,045.51 km) |
| Shepherdsville to Sheboygan (Wisconsin) | 411.78 mi (662.70 km) |
| Shepherdsville to Shelby (North Carolina) | 296.00 mi (476.37 km) |
| Shepherdsville to Shelbyville (Indiana) | 107.45 mi (172.92 km) |
| Shepherdsville to Shelbyville (Kentucky) | 30.00 mi (48.28 km) |
