| Shepherdsville to Orangeburg (South Carolina) | 411.77 mi (662.68 km) |
| Shepherdsville to Orangevale (California) | 1,913.55 mi (3,079.56 km) |
| Shepherdsville to Orchards (Washington) | 1,950.35 mi (3,138.79 km) |
| Shepherdsville to Orcutt (California) | 1,931.06 mi (3,107.75 km) |
| Shepherdsville to Oregon (Ohio) | 280.74 mi (451.81 km) |
| Shepherdsville to Oregon (Wisconsin) | 392.70 mi (631.99 km) |
| Shepherdsville to Oregon City (Oregon) | 1,952.39 mi (3,142.07 km) |
| Shepherdsville to Orem (Utah) | 1,397.35 mi (2,248.82 km) |
| Shepherdsville to Orinda (California) | 1,975.00 mi (3,178.45 km) |
| Shepherdsville to Orland Park (Illinois) | 275.54 mi (443.44 km) |
| Shepherdsville to Orlando (Florida) | 703.18 mi (1,131.67 km) |
| Shepherdsville to Ormond Beach (Florida) | 655.42 mi (1,054.80 km) |
| Shepherdsville to Oro Valley (Arizona) | 1,472.74 mi (2,370.15 km) |
| Shepherdsville to Oroville (California) | 1,922.78 mi (3,094.41 km) |
| Shepherdsville to Oshkosh (Wisconsin) | 443.20 mi (713.27 km) |
