| Shepherdsville to Olympia (Washington) | 1,973.79 mi (3,176.51 km) |
| Shepherdsville to Olympia Heights (Florida) | 903.01 mi (1,453.25 km) |
| Shepherdsville to Omaha (Nebraska) | 595.28 mi (958.01 km) |
| Shepherdsville to On Top of the World Designated Place (Florida) | 643.84 mi (1,036.16 km) |
| Shepherdsville to Onalaska (Wisconsin) | 498.93 mi (802.95 km) |
| Shepherdsville to Oneida (New York) | 633.24 mi (1,019.10 km) |
| Shepherdsville to Oneonta (New York) | 639.87 mi (1,029.78 km) |
| Shepherdsville to Ontario (California) | 1,794.97 mi (2,888.73 km) |
| Shepherdsville to Ontario (Oregon) | 1,672.42 mi (2,691.50 km) |
| Shepherdsville to Opa-locka (Florida) | 893.27 mi (1,437.57 km) |
| Shepherdsville to Opelika (Alabama) | 368.04 mi (592.30 km) |
| Shepherdsville to Opelousas (Louisiana) | 630.63 mi (1,014.91 km) |
| Shepherdsville to Orange (California) | 1,811.79 mi (2,915.80 km) |
| Shepherdsville to Orange (Texas) | 711.91 mi (1,145.71 km) |
| Shepherdsville to Orange City (Florida) | 674.59 mi (1,085.64 km) |
