| Shepherdsville to Elyria (Ohio) | 302.52 mi (486.85 km) |
| Shepherdsville to Emeryville (California) | 1,981.69 mi (3,189.23 km) |
| Shepherdsville to Emmaus (Pennsylvania) | 573.25 mi (922.56 km) |
| Shepherdsville to Emporia (Kansas) | 570.21 mi (917.67 km) |
| Shepherdsville to Encinitas (California) | 1,798.40 mi (2,894.24 km) |
| Shepherdsville to Endicott (New York) | 583.23 mi (938.63 km) |
| Shepherdsville to Endwell (New York) | 585.79 mi (942.73 km) |
| Shepherdsville to Englewood (Colorado) | 1,043.01 mi (1,678.57 km) |
| Shepherdsville to Englewood (Florida) | 785.16 mi (1,263.59 km) |
| Shepherdsville to Englewood (New Jersey) | 656.69 mi (1,056.84 km) |
| Shepherdsville to Englewood (Ohio) | 150.13 mi (241.60 km) |
| Shepherdsville to Enid (Oklahoma) | 678.06 mi (1,091.23 km) |
| Shepherdsville to Ennis (Texas) | 730.13 mi (1,175.03 km) |
| Shepherdsville to Ensley (Florida) | 522.86 mi (841.47 km) |
| Shepherdsville to Enterprise (Alabama) | 459.81 mi (739.99 km) |
