| Shepherdsville to Des Plaines (Illinois) | 303.26 mi (488.05 km) |
| Shepherdsville to Desert Hot Springs (California) | 1,738.87 mi (2,798.43 km) |
| Shepherdsville to DeSoto (Texas) | 730.37 mi (1,175.42 km) |
| Shepherdsville to Destin (Florida) | 526.00 mi (846.51 km) |
| Shepherdsville to Destrehan (Louisiana) | 614.96 mi (989.69 km) |
| Shepherdsville to Detroit (Michigan) | 333.60 mi (536.88 km) |
| Shepherdsville to Diamond Bar (California) | 1,807.25 mi (2,908.49 km) |
| Shepherdsville to Diamond Springs (California) | 1,893.21 mi (3,046.83 km) |
| Shepherdsville to Dickinson (North Dakota) | 1,063.34 mi (1,711.28 km) |
| Shepherdsville to Dickinson (Texas) | 796.79 mi (1,282.30 km) |
| Shepherdsville to Dickson (Tennessee) | 161.23 mi (259.48 km) |
| Shepherdsville to Difficult Run (Virginia) | 456.35 mi (734.43 km) |
| Shepherdsville to Dinuba (California) | 1,845.55 mi (2,970.13 km) |
| Shepherdsville to Discovery Bay (California) | 1,943.66 mi (3,128.02 km) |
| Shepherdsville to Dix Hills (New York) | 687.66 mi (1,106.68 km) |
