| Shasta Lake to Enterprise (Nevada) | 503.89 mi (810.93 km) |
| Shasta Lake to Enumclaw (Washington) | 451.09 mi (725.96 km) |
| Shasta Lake to Ephrata (Pennsylvania) | 2,401.21 mi (3,864.37 km) |
| Shasta Lake to Erie (Colorado) | 912.39 mi (1,468.34 km) |
| Shasta Lake to Erie (Pennsylvania) | 2,172.29 mi (3,495.96 km) |
| Shasta Lake to Erlanger (Kentucky) | 1,992.61 mi (3,206.79 km) |
| Shasta Lake to Escanaba (Michigan) | 1,795.88 mi (2,890.18 km) |
| Shasta Lake to Escondido (California) | 597.71 mi (961.92 km) |
| Shasta Lake to Española (New Mexico) | 939.23 mi (1,511.54 km) |
| Shasta Lake to Essex (Maryland) | 2,405.34 mi (3,871.02 km) |
| Shasta Lake to Essex Junction (Vermont) | 2,481.84 mi (3,994.14 km) |
| Shasta Lake to Estelle (Louisiana) | 1,954.82 mi (3,145.98 km) |
| Shasta Lake to Estero (Florida) | 2,508.43 mi (4,036.93 km) |
| Shasta Lake to Euclid (Ohio) | 2,107.09 mi (3,391.03 km) |
| Shasta Lake to Eufaula (Alabama) | 2,142.10 mi (3,447.37 km) |
