| Shaker Heights to Enterprise (Nevada) | 1,841.62 mi (2,963.79 km) |
| Shaker Heights to Enumclaw (Washington) | 2,013.75 mi (3,240.82 km) |
| Shaker Heights to Ephrata (Pennsylvania) | 294.49 mi (473.93 km) |
| Shaker Heights to Erie (Colorado) | 1,229.60 mi (1,978.85 km) |
| Shaker Heights to Erie (Pennsylvania) | 88.05 mi (141.70 km) |
| Shaker Heights to Erlanger (Kentucky) | 233.68 mi (376.08 km) |
| Shaker Heights to Escanaba (Michigan) | 404.77 mi (651.41 km) |
| Shaker Heights to Escondido (California) | 2,019.69 mi (3,250.38 km) |
| Shaker Heights to Española (New Mexico) | 1,369.13 mi (2,203.40 km) |
| Shaker Heights to Essex (Maryland) | 307.65 mi (495.11 km) |
| Shaker Heights to Essex Junction (Vermont) | 474.25 mi (763.24 km) |
| Shaker Heights to Estelle (Louisiana) | 934.89 mi (1,504.56 km) |
| Shaker Heights to Estero (Florida) | 1,039.73 mi (1,673.28 km) |
| Shaker Heights to Euclid (Ohio) | 8.16 mi (13.14 km) |
| Shaker Heights to Eufaula (Alabama) | 690.10 mi (1,110.60 km) |
