| Sebring to Southern Pines (North Carolina) | 546.60 mi (879.67 km) |
| Sebring to Southfield (Michigan) | 1,041.33 mi (1,675.86 km) |
| Sebring to Southgate (Michigan) | 1,022.36 mi (1,645.33 km) |
| Sebring to Southlake (Texas) | 1,009.39 mi (1,624.46 km) |
| Sebring to Spanaway (Washington) | 2,586.82 mi (4,163.08 km) |
| Sebring to Spanish Fork (Utah) | 1,927.66 mi (3,102.27 km) |
| Sebring to Spanish Lake (Missouri) | 930.24 mi (1,497.07 km) |
| Sebring to Spanish Springs (Nevada) | 2,334.52 mi (3,757.04 km) |
| Sebring to Sparks (Nevada) | 2,336.05 mi (3,759.51 km) |
| Sebring to Spartanburg (South Carolina) | 516.68 mi (831.52 km) |
| Sebring to Spearfish (South Dakota) | 1,705.38 mi (2,744.54 km) |
| Sebring to Speedway (Indiana) | 894.20 mi (1,439.08 km) |
| Sebring to Spencer (Iowa) | 1,326.10 mi (2,134.16 km) |
| Sebring to Spokane (Washington) | 2,380.63 mi (3,831.25 km) |
| Sebring to Spokane Valley (Washington) | 2,372.01 mi (3,817.37 km) |
