| Seal Beach to Scottsbluff (Nebraska) | 963.78 mi (1,551.06 km) |
| Seal Beach to Scottsboro (Alabama) | 1,823.27 mi (2,934.27 km) |
| Seal Beach to Scottsdale (Arizona) | 356.64 mi (573.96 km) |
| Seal Beach to Scranton (Pennsylvania) | 2,356.88 mi (3,793.04 km) |
| Seal Beach to Seabrook (Maryland) | 2,301.83 mi (3,704.43 km) |
| Seal Beach to Seabrook (Texas) | 1,382.69 mi (2,225.22 km) |
| Seal Beach to Seaford (New York) | 2,472.06 mi (3,978.40 km) |
| Seal Beach to Seagoville (Texas) | 1,244.53 mi (2,002.87 km) |
| Seal Beach to Searcy (Arkansas) | 1,498.80 mi (2,412.09 km) |
| Seal Beach to Seaside (California) | 289.91 mi (466.56 km) |
| Seal Beach to SeaTac (Washington) | 971.16 mi (1,562.93 km) |
| Seal Beach to Seattle (Washington) | 983.28 mi (1,582.43 km) |
| Seal Beach to Sebastian (Florida) | 2,256.75 mi (3,631.88 km) |
| Seal Beach to Sebring (Florida) | 2,208.25 mi (3,553.84 km) |
| Seal Beach to Secaucus (New Jersey) | 2,441.63 mi (3,929.42 km) |
