| Seaford to Southern Pines (North Carolina) | 3,957.43 mi (6,368.87 km) |
| Seaford to Southfield (Michigan) | 3,783.47 mi (6,088.90 km) |
| Seaford to Southgate (Michigan) | 3,793.33 mi (6,104.78 km) |
| Seaford to Southlake (Texas) | 4,784.27 mi (7,699.54 km) |
| Seaford to Spanaway (Washington) | 4,862.08 mi (7,824.77 km) |
| Seaford to Spanish Fork (Utah) | 4,929.37 mi (7,933.06 km) |
| Seaford to Spanish Lake (Missouri) | 4,224.66 mi (6,798.93 km) |
| Seaford to Spanish Springs (Nevada) | 5,207.47 mi (8,380.62 km) |
| Seaford to Sparks (Nevada) | 5,213.62 mi (8,390.51 km) |
| Seaford to Spartanburg (South Carolina) | 4,073.88 mi (6,556.28 km) |
| Seaford to Spearfish (South Dakota) | 4,439.67 mi (7,144.97 km) |
| Seaford to Speedway (Indiana) | 4,022.31 mi (6,473.29 km) |
| Seaford to Spencer (Iowa) | 4,202.57 mi (6,763.38 km) |
| Seaford to Spokane (Washington) | 4,693.46 mi (7,553.40 km) |
| Seaford to Spokane Valley (Washington) | 4,688.12 mi (7,544.79 km) |
