| Scottsbluff to Silver Firs (Washington) | 992.35 mi (1,597.03 km) |
| Scottsbluff to Silver Spring (Maryland) | 1,409.17 mi (2,267.84 km) |
| Scottsbluff to Silver Springs Shores (Florida) | 1,496.06 mi (2,407.68 km) |
| Scottsbluff to Silverdale (Washington) | 1,012.02 mi (1,628.69 km) |
| Scottsbluff to Silverton (Oregon) | 980.90 mi (1,578.60 km) |
| Scottsbluff to Simi Valley (California) | 972.18 mi (1,564.58 km) |
| Scottsbluff to Simpsonville (South Carolina) | 1,256.73 mi (2,022.52 km) |
| Scottsbluff to Sioux City (Iowa) | 374.69 mi (603.01 km) |
| Scottsbluff to Sioux Falls (South Dakota) | 370.22 mi (595.81 km) |
| Scottsbluff to Skokie (Illinois) | 817.03 mi (1,314.88 km) |
| Scottsbluff to Sleepy Hollow (New York) | 1,535.16 mi (2,470.60 km) |
| Scottsbluff to Slidell (Louisiana) | 1,111.06 mi (1,788.07 km) |
| Scottsbluff to Smithfield (North Carolina) | 1,427.82 mi (2,297.85 km) |
| Scottsbluff to Smithfield (Utah) | 420.06 mi (676.02 km) |
| Scottsbluff to Smithville (Missouri) | 505.97 mi (814.28 km) |
