| Scottsbluff to Enterprise (Nevada) | 740.78 mi (1,192.17 km) |
| Scottsbluff to Enumclaw (Washington) | 972.06 mi (1,564.38 km) |
| Scottsbluff to Ephrata (Pennsylvania) | 1,431.04 mi (2,303.03 km) |
| Scottsbluff to Erie (Colorado) | 145.34 mi (233.90 km) |
| Scottsbluff to Erie (Pennsylvania) | 1,207.57 mi (1,943.40 km) |
| Scottsbluff to Erlanger (Kentucky) | 1,020.09 mi (1,641.67 km) |
| Scottsbluff to Escanaba (Michigan) | 866.80 mi (1,394.97 km) |
| Scottsbluff to Escondido (California) | 949.04 mi (1,527.34 km) |
| Scottsbluff to Española (New Mexico) | 425.26 mi (684.39 km) |
| Scottsbluff to Essex (Maryland) | 1,433.00 mi (2,306.18 km) |
| Scottsbluff to Essex Junction (Vermont) | 1,540.65 mi (2,479.43 km) |
| Scottsbluff to Estelle (Louisiana) | 1,122.65 mi (1,806.74 km) |
| Scottsbluff to Estero (Florida) | 1,634.89 mi (2,631.10 km) |
| Scottsbluff to Euclid (Ohio) | 1,138.76 mi (1,832.66 km) |
| Scottsbluff to Eufaula (Alabama) | 1,228.58 mi (1,977.20 km) |
