| Sayville to Enterprise (Nevada) | 2,283.92 mi (3,675.61 km) |
| Sayville to Enumclaw (Washington) | 2,431.24 mi (3,912.70 km) |
| Sayville to Ephrata (Pennsylvania) | 167.44 mi (269.47 km) |
| Sayville to Erie (Colorado) | 1,672.95 mi (2,692.36 km) |
| Sayville to Erie (Pennsylvania) | 374.09 mi (602.03 km) |
| Sayville to Erlanger (Kentucky) | 621.09 mi (999.55 km) |
| Sayville to Escanaba (Michigan) | 783.51 mi (1,260.94 km) |
| Sayville to Escondido (California) | 2,458.87 mi (3,957.17 km) |
| Sayville to Española (New Mexico) | 1,805.46 mi (2,905.61 km) |
| Sayville to Essex (Maryland) | 203.94 mi (328.20 km) |
| Sayville to Essex Junction (Vermont) | 258.58 mi (416.14 km) |
| Sayville to Estelle (Louisiana) | 1,216.25 mi (1,957.36 km) |
| Sayville to Estero (Florida) | 1,107.77 mi (1,782.79 km) |
| Sayville to Euclid (Ohio) | 442.37 mi (711.92 km) |
| Sayville to Eufaula (Alabama) | 906.12 mi (1,458.26 km) |
