| Santander to Roznava | 1,214.72 mi (1,954.91 km) |
| Santander to Ruzomberok | 1,164.62 mi (1,874.27 km) |
| Santander to Sabinov | 1,244.19 mi (2,002.33 km) |
| Santander to Sal'a | 1,089.14 mi (1,752.80 km) |
| Santander to Samorin | 1,061.99 mi (1,709.10 km) |
| Santander to Senec | 1,068.23 mi (1,719.15 km) |
| Santander to Senica | 1,072.74 mi (1,726.40 km) |
| Santander to Sered' | 1,084.09 mi (1,744.67 km) |
| Santander to Skalica | 1,068.83 mi (1,720.12 km) |
| Santander to Smizany | 1,217.68 mi (1,959.67 km) |
| Santander to Snina | 1,291.07 mi (2,077.77 km) |
| Santander to Spisska Nova Ves | 1,219.27 mi (1,962.23 km) |
| Santander to Stara L'ubovna | 1,228.36 mi (1,976.85 km) |
| Santander to Stara Tura | 1,088.78 mi (1,752.22 km) |
| Santander to Stropkov | 1,270.49 mi (2,044.66 km) |
