| Santander to Sangeorgiu de Mures | 1,389.81 mi (2,236.68 km) |
| Santander to Sangeorz-Bai | 1,399.42 mi (2,252.14 km) |
| Santander to Sannicolau Mare | 1,206.39 mi (1,941.50 km) |
| Santander to Santana | 1,248.78 mi (2,009.72 km) |
| Santander to Satu Mare | 1,316.98 mi (2,119.48 km) |
| Santander to Scobinti | 1,504.84 mi (2,421.80 km) |
| Santander to Scornicesti | 1,403.88 mi (2,259.33 km) |
| Santander to Sebes | 1,348.43 mi (2,170.09 km) |
| Santander to Seini | 1,335.16 mi (2,148.74 km) |
| Santander to Sfantu-Gheorghe | 1,455.24 mi (2,341.98 km) |
| Santander to Sibiu | 1,376.98 mi (2,216.04 km) |
| Santander to Sighetu Marmatiei | 1,363.89 mi (2,194.97 km) |
| Santander to Sighisoara | 1,406.09 mi (2,262.88 km) |
| Santander to Simeria | 1,321.87 mi (2,127.35 km) |
| Santander to Sinaia | 1,446.81 mi (2,328.41 km) |
