| Santander to Savignano sul Rubicone | 807.97 mi (1,300.30 km) |
| Santander to Savona | 614.01 mi (988.15 km) |
| Santander to Scafati | 955.98 mi (1,538.51 km) |
| Santander to Scalea | 1,040.51 mi (1,674.54 km) |
| Santander to Scandiano | 723.23 mi (1,163.92 km) |
| Santander to Scandicci | 749.39 mi (1,206.03 km) |
| Santander to Schio | 760.78 mi (1,224.35 km) |
| Santander to Sciacca | 976.05 mi (1,570.80 km) |
| Santander to Scicli | 1,077.78 mi (1,734.52 km) |
| Santander to Scordia | 1,067.14 mi (1,717.40 km) |
| Santander to Scorze | 796.05 mi (1,281.12 km) |
| Santander to Sedico | 799.69 mi (1,286.98 km) |
| Santander to Sedriano | 644.23 mi (1,036.79 km) |
| Santander to Segni | 863.18 mi (1,389.15 km) |
| Santander to Segrate | 660.06 mi (1,062.27 km) |
