| Santa Maria de Cayon to Olympia Heights (Florida) | 4,366.53 mi (7,027.26 km) |
| Santa Maria de Cayon to Omaha (Nebraska) | 4,452.61 mi (7,165.79 km) |
| Santa Maria de Cayon to On Top of the World Designated Place (Florida) | 4,321.07 mi (6,954.10 km) |
| Santa Maria de Cayon to Onalaska (Wisconsin) | 4,146.75 mi (6,673.56 km) |
| Santa Maria de Cayon to Oneida (New York) | 3,497.73 mi (5,629.05 km) |
| Santa Maria de Cayon to Oneonta (New York) | 3,490.03 mi (5,616.66 km) |
| Santa Maria de Cayon to Ontario (California) | 5,657.95 mi (9,105.59 km) |
| Santa Maria de Cayon to Ontario (Oregon) | 5,130.88 mi (8,257.36 km) |
| Santa Maria de Cayon to Opa-locka (Florida) | 4,355.01 mi (7,008.71 km) |
| Santa Maria de Cayon to Opelika (Alabama) | 4,323.99 mi (6,958.78 km) |
| Santa Maria de Cayon to Opelousas (Louisiana) | 4,727.44 mi (7,608.08 km) |
| Santa Maria de Cayon to Orange (California) | 5,678.30 mi (9,138.34 km) |
| Santa Maria de Cayon to Orange (Texas) | 4,822.87 mi (7,761.66 km) |
| Santa Maria de Cayon to Orange City (Florida) | 4,279.59 mi (6,887.33 km) |
| Santa Maria de Cayon to Orangeburg (South Carolina) | 4,077.19 mi (6,561.60 km) |
