| Santa Margarita to Scottsboro (Alabama) | 4,707.30 mi (7,575.67 km) |
| Santa Margarita to Scottsdale (Arizona) | 5,885.10 mi (9,471.16 km) |
| Santa Margarita to Scranton (Pennsylvania) | 3,984.17 mi (6,411.90 km) |
| Santa Margarita to Seabrook (Maryland) | 4,117.31 mi (6,626.17 km) |
| Santa Margarita to Seabrook (Texas) | 5,337.44 mi (8,589.78 km) |
| Santa Margarita to Seaford (New York) | 3,905.48 mi (6,285.26 km) |
| Santa Margarita to Seagoville (Texas) | 5,274.85 mi (8,489.04 km) |
| Santa Margarita to Seal Beach (California) | 6,124.11 mi (9,855.80 km) |
| Santa Margarita to Searcy (Arkansas) | 4,947.24 mi (7,961.82 km) |
| Santa Margarita to Seaside (California) | 6,109.20 mi (9,831.80 km) |
| Santa Margarita to SeaTac (Washington) | 5,545.61 mi (8,924.80 km) |
| Santa Margarita to Seattle (Washington) | 5,536.96 mi (8,910.87 km) |
| Santa Margarita to Sebastian (Florida) | 4,701.77 mi (7,566.77 km) |
| Santa Margarita to Sebring (Florida) | 4,762.66 mi (7,664.76 km) |
| Santa Margarita to Secaucus (New Jersey) | 3,928.95 mi (6,323.03 km) |
