| Santa Margarita to Orangevale (California) | 5,978.03 mi (9,620.71 km) |
| Santa Margarita to Orchards (Washington) | 5,646.39 mi (9,086.98 km) |
| Santa Margarita to Orcutt (California) | 6,152.78 mi (9,901.95 km) |
| Santa Margarita to Oregon (Ohio) | 4,329.26 mi (6,967.27 km) |
| Santa Margarita to Oregon (Wisconsin) | 4,543.59 mi (7,312.20 km) |
| Santa Margarita to Oregon City (Oregon) | 5,666.88 mi (9,119.96 km) |
| Santa Margarita to Orem (Utah) | 5,554.15 mi (8,938.55 km) |
| Santa Margarita to Orinda (California) | 6,054.10 mi (9,743.13 km) |
| Santa Margarita to Orland Park (Illinois) | 4,526.48 mi (7,284.67 km) |
| Santa Margarita to Orlando (Florida) | 4,717.53 mi (7,592.13 km) |
| Santa Margarita to Ormond Beach (Florida) | 4,673.77 mi (7,521.71 km) |
| Santa Margarita to Oro Valley (Arizona) | 5,911.27 mi (9,513.27 km) |
| Santa Margarita to Oroville (California) | 5,946.39 mi (9,569.79 km) |
| Santa Margarita to Oshkosh (Wisconsin) | 4,468.14 mi (7,190.78 km) |
| Santa Margarita to Oskaloosa (Iowa) | 4,744.82 mi (7,636.04 km) |
