| Santa Margarita to Odessa (Texas) | 5,568.77 mi (8,962.08 km) |
| Santa Margarita to Ogden (Utah) | 5,518.75 mi (8,881.57 km) |
| Santa Margarita to Oildale (California) | 6,072.42 mi (9,772.61 km) |
| Santa Margarita to Ojus (Florida) | 4,757.39 mi (7,656.28 km) |
| Santa Margarita to Okemos (Michigan) | 4,336.13 mi (6,978.33 km) |
| Santa Margarita to Oklahoma City (Oklahoma) | 5,196.75 mi (8,363.37 km) |
| Santa Margarita to Okmulgee (Oklahoma) | 5,123.95 mi (8,246.20 km) |
| Santa Margarita to Olathe (Kansas) | 4,935.40 mi (7,942.76 km) |
| Santa Margarita to Old Jamestown (Missouri) | 4,738.40 mi (7,625.72 km) |
| Santa Margarita to Oldsmar (Florida) | 4,800.98 mi (7,726.44 km) |
| Santa Margarita to Olean (New York) | 4,089.71 mi (6,581.75 km) |
| Santa Margarita to Olive Branch (Mississippi) | 4,871.96 mi (7,840.67 km) |
| Santa Margarita to Olivehurst (California) | 5,968.62 mi (9,605.56 km) |
| Santa Margarita to Olney (Maryland) | 4,122.25 mi (6,634.12 km) |
| Santa Margarita to Olympia (Washington) | 5,584.89 mi (8,988.01 km) |
