| Santa Margarita to Enumclaw (Washington) | 5,549.30 mi (8,930.74 km) |
| Santa Margarita to Ephrata (Pennsylvania) | 4,046.81 mi (6,512.71 km) |
| Santa Margarita to Erie (Colorado) | 5,309.64 mi (8,545.03 km) |
| Santa Margarita to Erie (Pennsylvania) | 4,162.87 mi (6,699.50 km) |
| Santa Margarita to Erlanger (Kentucky) | 4,475.37 mi (7,202.42 km) |
| Santa Margarita to Escanaba (Michigan) | 4,345.05 mi (6,992.69 km) |
| Santa Margarita to Escondido (California) | 6,118.06 mi (9,846.07 km) |
| Santa Margarita to Española (New Mexico) | 5,537.60 mi (8,911.91 km) |
| Santa Margarita to Essex (Maryland) | 4,087.63 mi (6,578.41 km) |
| Santa Margarita to Essex Junction (Vermont) | 3,776.66 mi (6,077.94 km) |
| Santa Margarita to Estelle (Louisiana) | 5,092.50 mi (8,195.59 km) |
| Santa Margarita to Estero (Florida) | 4,821.55 mi (7,759.53 km) |
| Santa Margarita to Euclid (Ohio) | 4,245.58 mi (6,832.60 km) |
| Santa Margarita to Eufaula (Alabama) | 4,770.83 mi (7,677.91 km) |
| Santa Margarita to Eugene (Oregon) | 5,752.19 mi (9,257.25 km) |
