| Santa Margarita to Emeryville (California) | 6,060.30 mi (9,753.12 km) |
| Santa Margarita to Emmaus (Pennsylvania) | 4,003.61 mi (6,443.18 km) |
| Santa Margarita to Emporia (Kansas) | 5,014.60 mi (8,070.22 km) |
| Santa Margarita to Encinitas (California) | 6,129.74 mi (9,864.86 km) |
| Santa Margarita to Endicott (New York) | 3,981.08 mi (6,406.93 km) |
| Santa Margarita to Endwell (New York) | 3,978.53 mi (6,402.82 km) |
| Santa Margarita to Englewood (Colorado) | 5,325.79 mi (8,571.03 km) |
| Santa Margarita to Englewood (Florida) | 4,827.95 mi (7,769.84 km) |
| Santa Margarita to Englewood (New Jersey) | 3,921.23 mi (6,310.61 km) |
| Santa Margarita to Englewood (Ohio) | 4,431.79 mi (7,132.28 km) |
| Santa Margarita to Enid (Oklahoma) | 5,171.95 mi (8,323.45 km) |
| Santa Margarita to Ennis (Texas) | 5,293.06 mi (8,518.36 km) |
| Santa Margarita to Ensley (Florida) | 4,928.45 mi (7,931.57 km) |
| Santa Margarita to Enterprise (Alabama) | 4,827.42 mi (7,768.99 km) |
| Santa Margarita to Enterprise (Nevada) | 5,900.51 mi (9,495.95 km) |
