| Santa Margarita to Sestao | 402.36 mi (647.54 km) |
| Santa Margarita to Sevilla | 520.23 mi (837.23 km) |
| Santa Margarita to Sevilla La Nueva | 379.87 mi (611.34 km) |
| Santa Margarita to Silla | 188.72 mi (303.72 km) |
| Santa Margarita to Silleda | 624.06 mi (1,004.33 km) |
| Santa Margarita to Sitges | 125.89 mi (202.60 km) |
| Santa Margarita to Socuellamos | 315.66 mi (508.00 km) |
| Santa Margarita to Soller | 21.89 mi (35.22 km) |
| Santa Margarita to Solsona | 178.68 mi (287.55 km) |
| Santa Margarita to Son Servera | 14.78 mi (23.79 km) |
| Santa Margarita to Sonseca | 374.87 mi (603.29 km) |
| Santa Margarita to Sopelana | 404.20 mi (650.50 km) |
| Santa Margarita to Soria | 324.52 mi (522.27 km) |
| Santa Margarita to Suances | 450.47 mi (724.96 km) |
| Santa Margarita to Sueca | 185.42 mi (298.41 km) |
