| Santa Clarita to University Place (Washington) | 908.87 mi (1,462.68 km) |
| Santa Clarita to Upland (California) | 52.03 mi (83.74 km) |
| Santa Clarita to Upper Arlington (Ohio) | 1,973.75 mi (3,176.45 km) |
| Santa Clarita to Upper Grand Lagoon (Florida) | 1,927.05 mi (3,101.29 km) |
| Santa Clarita to Upper Montclair (New Jersey) | 2,437.73 mi (3,923.14 km) |
| Santa Clarita to Urbana (Illinois) | 1,703.02 mi (2,740.74 km) |
| Santa Clarita to Urbana (Maryland) | 2,280.03 mi (3,669.35 km) |
| Santa Clarita to Urbana (Ohio) | 1,937.62 mi (3,118.31 km) |
| Santa Clarita to Urbandale (Iowa) | 1,428.56 mi (2,299.05 km) |
| Santa Clarita to Utica (New York) | 2,379.14 mi (3,828.86 km) |
| Santa Clarita to Uvalde (Texas) | 1,154.19 mi (1,857.48 km) |
| Santa Clarita to Vacaville (California) | 333.74 mi (537.10 km) |
| Santa Clarita to Vadnais Heights (Minnesota) | 1,528.49 mi (2,459.86 km) |
| Santa Clarita to Vail (Arizona) | 480.26 mi (772.90 km) |
| Santa Clarita to Valdosta (Georgia) | 2,053.64 mi (3,305.01 km) |
