| Santa Clarita to Storm Lake (Iowa) | 1,375.72 mi (2,214.00 km) |
| Santa Clarita to Storrs (Connecticut) | 2,533.95 mi (4,077.99 km) |
| Santa Clarita to Stoughton (Wisconsin) | 1,674.62 mi (2,695.03 km) |
| Santa Clarita to Stow (Ohio) | 2,060.19 mi (3,315.55 km) |
| Santa Clarita to Streamwood (Illinois) | 1,717.17 mi (2,763.52 km) |
| Santa Clarita to Streator (Illinois) | 1,676.10 mi (2,697.42 km) |
| Santa Clarita to Streetsboro (Ohio) | 2,064.87 mi (3,323.09 km) |
| Santa Clarita to Strongsville (Ohio) | 2,039.76 mi (3,282.68 km) |
| Santa Clarita to Stuart (Florida) | 2,310.01 mi (3,717.60 km) |
| Santa Clarita to Stuarts Draft (Virginia) | 2,197.21 mi (3,536.07 km) |
| Santa Clarita to Sturgis (Michigan) | 1,856.48 mi (2,987.71 km) |
| Santa Clarita to Suamico (Wisconsin) | 1,755.41 mi (2,825.07 km) |
| Santa Clarita to Sudley (Virginia) | 2,275.03 mi (3,661.31 km) |
| Santa Clarita to Suffern (New York) | 2,439.48 mi (3,925.97 km) |
| Santa Clarita to Suffolk (Virginia) | 2,339.39 mi (3,764.88 km) |
