| Santa Clarita to Stephenville (Texas) | 1,178.54 mi (1,896.67 km) |
| Santa Clarita to Sterling (Colorado) | 940.00 mi (1,512.79 km) |
| Santa Clarita to Sterling (Illinois) | 1,637.75 mi (2,635.70 km) |
| Santa Clarita to Sterling (Virginia) | 2,278.55 mi (3,666.98 km) |
| Santa Clarita to Sterling Heights (Michigan) | 1,982.81 mi (3,191.02 km) |
| Santa Clarita to Steubenville (Ohio) | 2,101.17 mi (3,381.51 km) |
| Santa Clarita to Stevens Point (Wisconsin) | 1,682.74 mi (2,708.10 km) |
| Santa Clarita to Stevenson Ranch (California) | 5.59 mi (8.99 km) |
| Santa Clarita to Stillwater (Minnesota) | 1,539.68 mi (2,477.88 km) |
| Santa Clarita to Stillwater (Oklahoma) | 1,211.69 mi (1,950.03 km) |
| Santa Clarita to Stockbridge (Georgia) | 1,955.07 mi (3,146.38 km) |
| Santa Clarita to Stockton (California) | 291.67 mi (469.40 km) |
| Santa Clarita to Stone Ridge (Virginia) | 2,270.95 mi (3,654.74 km) |
| Santa Clarita to Stonecrest (Georgia) | 1,958.11 mi (3,151.28 km) |
| Santa Clarita to Stony Brook (New York) | 2,493.28 mi (4,012.55 km) |
